Ulrich Dobrindt Selected Research

Virulence Factors (Pathogenicity Factors)

1/2020	ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia coli.
12/2019	Transcriptional and Translational Inhibitors Block SOS Response and Shiga Toxin Expression in Enterohemorrhagic Escherichia coli.
10/2019	Orthosipon stamineus extract exerts inhibition of bacterial adhesion and chaperon-usher system of uropathogenic Escherichia coli-a transcriptomic study.
1/2019	Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae.
1/2017	Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and mechanisms of cell injury.
12/2016	Iron Homeostasis Regulates the Genotoxicity of Escherichia coli That Produces Colibactin.
10/2016	Pertussis Toxin Exploits Host Cell Signaling Pathways Induced by Meningitis-Causing E. coli K1-RS218 and Enhances Adherence of Monocytic THP-1 Cells to Human Cerebral Endothelial Cells.
1/2015	Genomic avenue to avian colisepticemia.
12/2014	α-Haemolysin of Escherichia coli in IBD: a potentiator of inflammatory activity in the colon.
1/2014	Heteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis in Escherichia coli O2:H6.

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Ulrich Dobrindt Research Topics

Disease

17	Infections 01/2022 - 05/2008
12	Urinary Tract Infections (Urinary Tract Infection) 05/2021 - 01/2002
5	Neoplasms (Cancer) 12/2021 - 01/2019
3	Intestinal Diseases (Diseases, Intestinal) 01/2022 - 01/2017
3	Colorectal Neoplasms (Colorectal Cancer) 12/2021 - 01/2017
3	Carcinogenesis 02/2021 - 12/2016
3	Inflammation (Inflammations) 01/2021 - 12/2014
3	Colitis 12/2014 - 09/2002
2	Hemolytic-Uremic Syndrome 12/2019 - 09/2002
2	Bovine Mastitis 08/2019 - 06/2011
2	Sepsis (Septicemia) 01/2018 - 01/2015
2	Bacterial Infections (Bacterial Infection) 09/2008 - 11/2006
1	Foreign Bodies (Foreign Body) 05/2021
1	Chromosome Aberrations (Chromosome Abnormalities) 02/2021
1	Adenocarcinoma 02/2021
1	Colonic Neoplasms (Colon Cancer) 01/2021
1	Multiple Sclerosis 01/2021
1	Exocrine Pancreatic Insufficiency 12/2020
1	Genomic Instability 10/2020
1	Escherichia coli Infections 01/2020
1	Oncogene Addiction 01/2019
1	Meningitis 10/2016
1	Whooping Cough (Pertussis) 10/2016
1	Carcinoma (Carcinomatosis) 01/2016
1	Diarrhea 01/2014
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2012
1	Prostatitis 06/2011
1	Mastitis 06/2011
1	Chromosomal Instability (Chromosome Stability) 02/2011
1	Typhoid Fever (Typhoid) 12/2008
1	Bacteriuria 02/2008
1	Necrosis 10/2007
1	Salmonella Infections (Salmonellosis) 10/2006
1	Pyelonephritis 04/2006

Drug/Important Bio-Agent (IBA)

14	Virulence Factors (Pathogenicity Factors)IBA 01/2020 - 01/2002
7	Anti-Bacterial Agents (Antibiotics)IBA 05/2021 - 10/2008
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2016
4	colibactinIBA 12/2021 - 01/2017
3	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 09/2008
2	ZincIBA 10/2021 - 01/2017
2	MutagensIBA 02/2021 - 01/2017
2	Bacterial AdhesinsIBA 01/2016 - 04/2006
2	Shiga Toxin (Shigella Toxin)IBA 01/2014 - 09/2002
2	LipopolysaccharidesIBA 06/2011 - 12/2008
2	VaccinesIBA 05/2010 - 10/2006
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2006 - 07/2003
1	17-hydroxyestrane-3-carbonitrile (ECN)IBA 01/2022
1	7-hydroxycoumarin (umbelliferone)IBA 10/2021
1	nitroxolineIBA 05/2021
1	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 05/2021
1	Methylene Blue (Methylthioninium Chloride)FDA Link 02/2021
1	OligosaccharidesIBA 02/2021
1	Conjugated Linoleic AcidsIBA 01/2021
1	Protease La (Endopeptidase La)IBA 01/2021
1	Linoleic Acid (Linoleate)IBA 01/2021
1	Peptide Hydrolases (Proteases)FDA Link 01/2021
1	EnzymesIBA 12/2020
1	Nalidixic Acid FDA Link 12/2020
1	Antimicrobial PeptidesIBA 12/2020
1	cecropin AIBA 12/2020
1	MicroRNAs (MicroRNA)IBA 01/2020
1	Analgesics (Analgesic Drugs)IBA 01/2020
1	PolyketidesIBA 01/2020
1	Peptides (Polypeptides)IBA 01/2020
1	AlarminsIBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	IntegrasesIBA 01/2020
1	Shiga Toxins (Vero Toxin)IBA 12/2019
1	Photosensitizing Agents (Photosensitizers)IBA 07/2018
1	Histones (Histone)IBA 10/2017
1	Toll-Like Receptors (Toll-Like Receptor)IBA 10/2017
1	IronIBA 12/2016
1	Pertussis ToxinIBA 10/2016
1	IntegrinsIBA 01/2016
1	AntigensIBA 12/2014
1	Pharmaceutical PreparationsIBA 08/2014
1	Biological ProductsIBA 12/2011
1	O Antigens (O Antigen)IBA 06/2011
1	tellurous acid (tellurate)IBA 02/2011
1	PrebioticsIBA 05/2008
1	Interleukin-13IBA 10/2007
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 11/2006
1	Capsules (Microcapsules)IBA 10/2004
1	InterleukinsIBA 07/2003
1	Interleukin-10 (Interleukin 10)IBA 07/2003
1	Messenger RNA (mRNA)IBA 07/2003
1	InterferonsIBA 07/2003
1	Sorbitol (Yal)FDA Link 09/2002

Therapy/Procedure

2	Photochemotherapy (Photodynamic Therapy) 08/2019 - 07/2018
2	Kidney Transplantation 07/2019 - 01/2017
1	Indwelling Catheters (Indwelling Catheter) 05/2021
1	Therapeutics 05/2021
1	Enzyme Replacement Therapy 12/2020
1	Lasers (Laser) 12/2014
1	Oral Administration 11/2012